Houston Methodist Pharmacology Practice Exam - Practice Test and Study Guide

Streptokinase is a thrombolytic agent that is used to dissolve blood clots in various conditions, such as myocardial infarction and pulmonary embolism. One notable potential side effect of streptokinase is an allergic reaction. This occurs because streptokinase is derived from streptococci, and prior exposure to this bacterium can lead to the development of antibodies against it. An allergic reaction may present with symptoms such as rash, hives, or more severe anaphylactic symptoms, which can include difficulty breathing or swelling of the face and throat.

Understanding the risk of allergic reactions is important when administering streptokinase, particularly in patients with a history of streptococcal infections or previous treatment with streptokinase. Monitoring for signs of allergy during and after administration of the drug is essential to ensure patient safety.